After a pig heart transplant, man works to regain strength 

WASHINGTON

It’s been a month since a Maryland man became the second person to receive a transplanted heart from a pig – and hospital video released on Oct. 20 shows he’s working hard to recover.

Lawrence Faucette was dying from heart failure and ineligible for a traditional heart transplant because of other health problems when doctors at the University of Maryland School of Medicine offered the highly experimental surgery.

In the first glimpse of Faucette provided since the Sept. 20 transplant, hospital video shows physical therapist Chris Wells urging him to smile while pushing through a pedaling exercise to regain his strength.

“That’s going to be tough but I’ll work it out,” Faucette, 58, replied, breathing heavily but giving a smile.

The Maryland team last year performed the world’s first transplant of a heart from a genetically altered pig into another dying man.

David Bennett survived just two months before that heart failed, for reasons that aren’t completely clear although signs of a pig virus later were found inside the organ. Lessons from that first experiment led to changes before this second try, including better virus testing.

Attempts at animal-to-human organ transplants, called xenotransplants, have failed for decades, as people’s immune systems immediately destroyed the foreign tissue. Now scientists are trying again using pigs genetically modified to make their organs more humanlike.

In Friday’s hospital video, Faucette’s doctors said the pig heart has shown no sign of rejection.

“His heart is doing everything on its own,” said Dr. Muhammad Mohiuddin, the Maryland team’s cardiac xenotransplantation chief.

A hospital spokeswoman said Faucette, of Frederick, Maryland, has been able to stand and physical therapists are helping him gain strength needed to attempt walking.